ISSN: 2718-0085
Volume : 2 Issue : 1 Year : 2021
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Ophthalmoplegia in the Acute Phase of Hemolytic Uremic Syndrome: A Case Report [TIP]
TIP. 2021; 2(1): 47-50 | DOI: 10.5222/TP.2021.33042

Ophthalmoplegia in the Acute Phase of Hemolytic Uremic Syndrome: A Case Report

Müge Ayanoğlu1, Ferah Sönmez2, Ayse Tosun1, Dilek Yılmaz2
1Aydın Adnan Menderes University, School of Medicine, Department of Pediatric Neurology, Aydın, Turkey
2Aydın Adnan Menderes University, School of Medicine, Department of Pediatric Nephrology, Aydın, Turkey

Hemolytic uremic syndrome (HUS) is a common form of thrombotic microangiopathies. Among its extrarenal complications, ocular involvement is very rare.
We present a patient with HUS, whose first symptom was isolated abduction deficits in the eyes. Lethargy was added during the clinical course, suggesting neurological involvement. Although conventional magnetic resonance imaging was normal, symmetric diffusion restriction was detected in bilateral putamen on diffusion-weighted images. Treatment with peritoneal dialysis, fresh frozen plasma infusions, and eculizumab was initiated. The patient responded well to the treatment and was discharged with excellent neurological, hematological, and ophthalmological outcomes. Nephrological follow-up is being continued due to proteinuria
To our knowledge, presenting with ophthalmoplegia in the acute phase of hemolytic uremic syndrome is very rare. The patient’s ophthalmological and neurological symptoms improved after eculizumab treatment. We suggest that eculizumab is effective in the acute phase of HUS in cases of ophthalmological involvement.

Keywords: Ophthalmoplegia, hemolytic uremic syndrome, diffusion restriction, putamen, eculizumab

Müge Ayanoğlu, Ferah Sönmez, Ayse Tosun, Dilek Yılmaz. Ophthalmoplegia in the Acute Phase of Hemolytic Uremic Syndrome: A Case Report. TIP. 2021; 2(1): 47-50

Corresponding Author: Müge Ayanoğlu, Türkiye
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